REACH: Randomised trial Rehabilitation EArly for Congenital Hemiplegia
Chief Investigarors: CIs Boyd, Ziviani, Novak, Badawi, Elliott; AI Sakzewski.
Funding: NHMRC1078877 (2015-8) $938k.
Aims: To examine the efficacy of modified CIMT compared to an equal dose of traditional bimanual training (BIM) on early reaching and grasping and brain (re)organisation in 150 infants with asymmetric brain lesions who are at high risk of developing hemiplegia. Infants will be identified on neonatal ultrasound or MRI in a multisite
Randomised Controlled Trial (RCT): A total sample size of 150 (75 in each group) allows a difference ≥0.5 SD with α=0.05 and 80% power to be detected with 15% loss to f/u. Interventions: Both interventions commence at 3 months C.A. with a graduated intensity of training up until 12 months (total 84 hours), delivered at home by the parent supported by a paediatric OT/PT with Telehealth support.
Update: Recruitment has commenced in 4 states.
New knowledge: First RCT comparing two very early rehabilitation approaches for infant hemiplegia.
