Chief Investigators: Liley, Novak, Colditz, Badawi, Hunt, Jacobs.
Rationale: Even with hypothermia, 46% term infants with moderate to severe HIE die or survive with major NDD.
Design: Phase III RCT multi-centre trial EPO plus hypothermia improves outcomes following HIE at 2 years, compared to hypothermia alone.
Update: 27 sites have recruited 258/300.
New Knowledge: EPO has neuroprotective effects distinct from hypothermia & may be additive.
