Targeting the inflammasome: the key to curing cerebral palsy?

CI: Fahey. McDonald CPA 2018-2020 $105k.

Aims: Role of the inflammasome in perinatal brain injury and assess the effectiveness of novel inflammasome inhibitors to reduce perinatal brain injury83.

Mechanism: Anti-inflammatory.

New Knowledge: This novel pathway may identify a new target to “repurpose” already approved inhibitors for treatment of perinatal brain injury.

Project members

Associate Professor Michael Fahey

Director of Neurogenetics, Monash Paediatrics
Monash University
Head of Child Neurology
Monash Children’s Hospital