Stem cell treatment for neonatal hypoxic-ischemic encephalopathy (HIE)

National Health and Medical Research Council
CIs: Bjorkman, Colditz, (NHMRC1145450 $954k 2018-21; RCHF $240k 2017-2020).
Aims: Identify and optimise an effective stem cell therapy for neonatal HIE in combination with therapeutic hypothermia using MRI/MRS.
Mechanism: Anti-inflammatory & trophic.
New Knowledge: First pre-clinical study (piglets) to test the effectiveness of sorted placental stem cells as adjunct to cooling.