Optimising neurodevelopment outcomes for fetal growth restriction (FGR)

National Health and Medical Research Council

CIs: Jenkin, Malhotra. NHMRC1160393; 2019-22 $1.2M.

Aims: Effects of antenatal melatonin and/or postnatal UCB as neuroprotective treatments for growth restricted lambs.

Mechanism: Antioxidant, anti-inflammatory and anti-apoptotic.

New Knowledge: First trial to assess behavioural outcomes following growth restriction and ability of melatonin and/or UCB to rescue the brain.